The Gladstone Chamber of Commerce and Industry will launch the 2018 Boom Bust Recharge survey on Monday.
This study is a follow up report to the 2014 Boom or Bust and 2016 Boom, Bust or Reset studies undertaken by GCCI.
The Boom Bust Recharge study will include a more in-depth insight into how businesses are dealing with the digital world, and if changes in government regulations are providing opportunities.
These include the National Disability Insurance Scheme and and how mental health issues may be affecting local businesses.
GCCI president Carl Carter said it is an interesting time for the Gladstone region, with a number of business openings and closures since the first study was completed.
"We need many businesses to complete the survey so that we can see what is happening now in terms of business growth, as well as determine trends over the last six years," he said.
"We are looking forward to this year's survey as times have changed."
In the 2014 and 2016 studies, respondents were asked what their three biggest issues were.
The most common responses over both surveys included staff issues, decreased work, higher costs, government issues and not buying local.
"It will be interesting to see if the issues are the same," Mr Carter said.
"If they are, the Chamber will be advocating for more support from all levels of government and reassessing how the Chamber can assist businesses to overcome these issues."
The 2016 Boom, Bust or Reset became the biggest business study ever undertaken in the Gladstone region, reaching 253 local businesses.
This year a target of 300 surveys has been set.